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Indeed, the translocator protein (Tspo), a protein that binds to the voltage-dependent anion channel (VDAC) and interferes with redox balance 69,70,71 was upregulated after sUA+LPS stimulus in all macrophages analyzed, but in a more pronounced way in WT and Myd88 / cells

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However, it is important to note that adrenal burnout is not an official medical diagnosis, and the mechanisms involved may not directly involve the adrenals experiencing complete exhaustion (63)

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